Synergistic Enhancement of Itraconazole Dissolution by Ternary System Formation with Pluronic F68 and Hydroxypropylmethylcellulose
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چکیده
منابع مشابه
Dissolution Rate Enhancement of Clarithromycin Using Ternary Ground Mixtures: Nanocrystal Formation
Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...
متن کاملDissolution Rate Enhancement of Clarithromycin Using Ternary Ground Mixtures: Nanocrystal Formation
Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...
متن کاملdissolution rate enhancement of clarithromycin using ternary ground mixtures: nanocrystal formation
clarithromycin (cla), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. the aim of this investigation was to prepare cla nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (sls) and polyvinyl pyrrolidone (pvp) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. different weight rati...
متن کاملIncrease in Dissolution Rate of Simvastatin by Amorphous Solid Dispersion System with Hydroxypropylmethylcellulose Polymer
The objective of the present study was to prepare amorphous solid dispersion system simvastatin–hydroxypropylmethylcellulose (HPMC) to enhance the dissolution rate. Amorphous solid dispersion of simvastatin was prepared by solvent technique using HPMC as carrier with ratio of 1:1, 1:3 and 1:5 (w/w). Physicochemical properties of solid dispersions were investigated by X-ray powder diffraction, t...
متن کاملDissolution Rate Enhancement of Clarithromycin Using Ternary Ground Mixtures: Nanocrystal Formation
Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...
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ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2009
ISSN: 0036-8709
DOI: 10.3797/scipharm.0901-08